Cupric sulfate munyu wakagadzirwa nekurapa cupric oxide ne sulfuric acid.Izvi zvinoumba sehombe, yakajeka makristasi ebhuruu ane mamorekuru mashanu emvura (CuSO4∙5H2O) uye inozivikanwawo seblue vitriol.Iyo anhydrous munyu inogadzirwa nekudziisa iyo hydrate kusvika 150 °C (300 °F).